Folklore Clinical Variant Interpretation MCP

Overview

Folklore Clinical Variant Interpretation MCP is a Helena Bioinformatics server that brings ACMG/AMP evidence frameworks and clinical literature directly into your AI assistant. It interprets genetic variants in a clinical context, helping you evaluate pathogenicity and support variant classification with structured evidence.

This is a hosted remote server — connect your MCP client to https://api.helena.bio/folklore/v1/mcp with no local installation required. Version v1.4.1 is released under Apache-2.0, with full source code available at helena-bioinformatics/folklore-mcp on GitHub. No authentication is needed to get started.

You'll find Folklore in the Development category on mcp.site. It works with Claude Desktop, Claude Code, Cursor, VS Code, and other MCP clients. If you maintain this server, claim your listing to verify ownership and keep information current.

Installation

Settings → Connectors → Add custom connector
Name: Folklore Clinical Variant Interpretation MCP
URL:  https://api.helena.bio/folklore/v1/mcp