Orchestraprime

Overview

Orchestraprime is a Model Context Protocol server that brings regulatory intelligence and sanctions screening directly into Claude. It provides access to FDA, ICH, and EMA regulatory data alongside OFAC, EU, and UK sanctions screening—enabling AI assistants to perform compliance checks and regulatory lookups as callable tools without leaving your workflow.

The server runs locally on your machine via the npm package @orchestraprime/mcp-server, which communicates with Claude over stdio. No authentication is required; install it with npx -y @orchestraprime/mcp-server and it works immediately. The latest release is v2.0.1, with full source code available at OrchestraPrime/mcp-server on GitHub.

Orchestraprime is listed in the Development category on mcp.site and works with any MCP client, including Claude Desktop, Claude Code, Cursor, VS Code, Windsurf, and Zed. If you maintain Orchestraprime, claim this listing to verify ownership and keep the information up to date.

Installation

// claude_desktop_config.json
{
  "mcpServers": {
    "orchestraprime": {
      "command": "npx",
      "args": [
        "-y",
        "@orchestraprime/mcp-server"
      ]
    }
  }
}