OpenHCS

Overview

OpenHCS is a Model Context Protocol server that enables AI assistants to inspect, author, validate, and run high-content microscopy workflows. Any MCP-compatible client can call OpenHCS tools directly, letting the model decide when to use them during conversations or agent runs.

The server runs locally as the Python package openhcs, installed via uvx openhcs. It communicates over stdio and requires no credentials to get started. The latest release is v0.8.0, published under the MIT license. Source code is available at OpenHCSDev/OpenHCS on GitHub.

OpenHCS is categorized as AI & Agents on mcp.site and works with all MCP clients including Claude Desktop, Claude Code, Cursor, VS Code, Windsurf, Zed, and others. If you maintain OpenHCS, claim this listing to verify ownership and keep details up to date.

Installation

// claude_desktop_config.json
{
  "mcpServers": {
    "openhcs": {
      "command": "uvx",
      "args": [
        "openhcs"
      ]
    }
  }
}